Feng, Y. and Irvine, K.D. 2007. Fat and expanded act in parallel to regulate growth through Warts. Proc. Nat. Acad. Sci. USA, 104, 20362-20367. Xu, A. and Haines, N., Dlugosz, M., Rana, N.A., Takeuchi, H. Haltiwanger, R.S., and Irvine, K.D. 2007. In vitro reconstitution of the modulation of Drosophila Notch-ligand binding by Fringe. J. Biol. Chem. 282, 35153-35162. Stolz, A., Haines, N., Pich, A., Irvine, K. D., Hokke, C. H., Deelder, A. M., Gerardy-Schahn, R., Wuhrer, M. and Bakker, H. 2007. Distinct contributions of β4GalNAcTA and β4GalNAcTB to Drosophila glycosphingolipid biosynthesis. Glycoconjugate J., DOI 10.1007/s10719-007-9069-5. Major R. and Irvine KD. Localization and Requirement for Myosin II at the Dorsal-Ventral Compartment Boundary of the Drosophila Wing. Developmental Dynamics. 2006. 235:3051-3058. Cho, E, Feng, Y, Rauskolb, C, Maitra S, Fehon R, and Irvine KD. Delineation of a Fat tumor suppressor pathway. Nature Genetics. 2006. 38(10): 1142-1150. Mao Y, Rauskolb C, Cho E, Hu WL, Hayter H, Minihan, G, Katz FN, and Irvine KD. Dachs: an unconventional myosin that functions downstream of Fat to regulate growth, affinity and gene expression in Drosophila. Development 2006. 133: 2539-2551. Download Pdf Rogulja, D. and Irvine, K.D. Regulation of Cell Proliferation by a morphogen gradient. Cell 2005 123:449-461. Xu, A. Lei, L., and Irvine, K.D.. Regions of Drosophila Notch that contribute to ligand binding and ther modulatory influence of Fringe. J. Biol. Chem. 2005. 280: 30158-30165. Major, R. and Irvine, K.D. Influence of Notch on dorsal-ventral compartmentalization and actin organization in the Drosophila wing. Development 2005. 132: 3823-3833. Haines N, and Irvine, KD. Functional analysis of Drosophila ß1, 4-N-acetlygalactosaminyltransferases. Glycobiology. 2005 15(4): 335-346. Okajima T, Xu A, Lei L, and Irvine KD. Chaperone Activity of Protein O-Fucosyltransferase 1 Promotes Notch Receptor Folding. Science. 2005 February 3; 10.1126 Koles K, Irvine KD, and Panin VM. Functional characterization of Drosophila Sialyltrasferase. J. Biol. Chem. 2004 279:4346-4357 Cho E and Irvine KD. Action of fat, four-jointed, dachsous and dachs in distal-to-proximal wing signaling. Development 2004 131:4489-4500. Lei L, Xu A, Panin V and Irvine KD. An O-fucose site in the ligand binding domain inhibits Notch activation. Development 2003 130: 6411-6421. Okajima T, Xu A and Irvine KD. Modulation of Notch-ligand binding by Protein O-fucosyltransferase 1 and Fringe. J. Biol. Chem. 2003 278: 42340-50. Haines N and Irvine KD. Glycosylation regulates the Notch signaling pathway. Nature Reviews MCB 2003 4:786-797. Correia T, Papayannopoulos V, Panin V, Woronoff P, Jiang J, Vogt TF, and Irvine KD. Molecular genetic analysis of the glycosyltransferase Fringe in Drosophila. PNAS. 2003 100:6404-6409. Li Y, Lei L, Irvine KD, and Baker NE. Notch activity in neural cells triggered by a mutant allele with altered glycosylation. Development. 2003 130:2829-2840. Okajima T and Irvine KD. Regulation of Notch Signaling by O-Linked Fucose. Cell. 2002 111:893-904. Nakamura Y, Haines N, Chen J, Okajima T, Furukawa K, Urano T, Stanley P, Irvine KD, and Furukawa K. Identification of a Drosophila gene encoding xylosylprotein b4-galactosyltransferase that is essential for the synthesis of glycosaminoglycans and for morphogenesis. J. Biol. Chem. 2002 277:46280-46288. Grammont, M and Irvine, KD. Organizer activity of the polar cells during Drosophila oogenesis. Development. 2002 129:5131-5140. Panin VM, Shao L, Lei Liang, Moloney DJ, Irvine KD, and Haltiwanger RS. Notch ligands are substrates for EGF protein O-fucosyltransferase and Fringe. J. Biol. Chem. 2002 277: 29945-29952. Irvine KD and Rauskolb C. Boundaries in development: formation and function. Annu Rev Cell Dev Biol. 2001;17:189-214. Grammont M and Irvine KD. fringe and Notch specify polar cell fate during Drosophila oogenesis. Development. 2001 Jun;128(12):2243-53. Liu X, Grammont M, and Irvine KD. Roles for scalloped and vestigial in regulating cell affinity and interactions between the wing blade and the wing hinge. Dev Biol. 2000 Dec 15;228(2):287-303. Moloney DJ, Panin VM, Johnston SH, Chen J, Shao L, Wilson R, Wang Y, Stanley P, Irvine KD, Haltiwanger RS, and Vogt TF. Fringe is a glycosyltransferase that modifies Notch. Nature. 2000 Jul 27;406(6794):369-75. Rauskolb C, Correia T, and Irvine KD. Fringe-dependent separation of dorsal and ventral cells in the Drosophila wing. Nature. 1999 Sep 30;401(6752):476-80. Irvine KD. Fringe, Notch, and making developmental boundaries. Curr Opin Genet Dev. 1999 Aug;9(4):434-41. Rauskolb C and Irvine KD. Notch-mediated segmentation and growth control of the Drosophila leg. Dev Biol. 1999 Jun 15;210(2):339-50. Panin VM and Irvine KD. Modulators of Notch signaling. Semin Cell Dev Biol. 1998 Dec;9(6):609-17. Simmonds AJ, Liu X, Soanes KH, Krause HM, Irvine KD, and Bell JB. Molecular interactions between Vestigial and Scalloped promote wing formation in Drosophila. Genes Dev. 1998 Dec 15;12(24):3815-20. Papayannopoulos V, Tomlinson A, Panin VM, Rauskolb C, and Irvine KD. Dorsal-ventral signaling in the Drosophila eye. Science. 1998 Sep 25;281(5385):2031-4. Irvine KD and Vogt TF. Dorsal-ventral signaling in limb development. Curr Opin Cell Biol. 1997 Dec;9(6):867-76. Panin VM, Papayannopoulos V, Wilson R, and Irvine KD. Fringe modulates Notch-ligand interactions. Nature. 1997 Jun 26;387(6636):908-12. Johnston SH, Rauskolb C, Wilson R, Prabhakaran B, Irvine KD, and Vogt TF. A family of mammalian Fringe genes implicated in boundary determination and the Notch pathway. Development. 1997 Jun;124(11):2245-54. Kim J, Irvine KD, and Carroll SB. Cell recognition, signal induction, and symmetrical gene activation at the dorsal-ventral boundary of the developing Drosophila wing. Cell. 1995 Sep 8;82(5):795-802. Irvine KD and Wieschaus E. fringe, a Boundary-specific signaling molecule, mediates interactions between dorsal and ventral cells during Drosophila wing development. Cell. 1994 Nov 18;79(4):595-606. Irvine KD and Wieschaus E. Cell intercalation during Drosophila germband extension and its regulation by pair-rule segmentation genes. Development. 1994 Apr;120(4):827-41. Irvine KD, Botas J, Jha S, Mann RS, and Hogness DS. Negative autoregulation by Ultrabithorax controls the level and pattern of its expression. Development. 1993 Jan;117(1):387-99. Irvine KD, Helfand SL, and Hogness DS. The large upstream control region of the Drosophila homeotic gene Ultrabithorax. Development. 1991 Feb;111(2):407-24. Burke JM, Irvine KD, Kaneko KJ, Kerker BJ, Oettgen AB, Tierney WM, Williamson CL, Zaug AJ, and Cech TR. Role of conserved sequence elements 9L and 2 in self-splicing of the Tetrahymena ribosomal RNA precursor. Cell. 1986 Apr 25;45(2):167-76.